Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179631 | 0.83 | SLC6A2 (0.42) | MAPTMEN1KMT2AL3MBTL1SLC6A2 | |
| SCHEMBL2964452 | 0.76 | SMN1; SMN2 (0.51) | MEN1KMT2AL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL5427925 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL5178886 | 0.74 | ALDH1A1 (0.53) | L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL5178842 | 0.74 | CYP1A2 (0.52) | MAPTMEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL27510900 | 0.73 | MAPT (0.53) | MAPTMEN1KMT2AL3MBTL1SLC6A2 | |
| SCHEMBL550320 | 0.70 | KMT2A (0.50) | MAPTMEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL5429351 | 0.70 | PKM (0.49) | MAPTMEN1KMT2ASLC6A2SLC6A4 | |
| Iodide SCHEMBL29459706 | 0.69 | KMT2A (0.49) | MAPTMEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL4441083 | 0.68 | SLC6A2 (0.64) | MAPTMEN1KMT2AL3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277726-B1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | NIHON NOHYAKU CO LTD (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-7057067-B2 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1277726-A1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | Nihon Nohyaku Co., Ltd. (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | HAO2, CBR1, AOC2 | MAPT 4716/4885MEN1 3539/4885KMT2A 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.