Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.47 |
| ▸ | ME1 | P48163 | 1/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560460 | 0.78 | NR1H2 (0.51) | PTGS2NR1H2NR1H3RAB9AADORA2A | |
| SCHEMBL30320663 | 0.76 | NR1H2 (0.71) | NR1H2NR1H3RAB9ACMA1GSK3A | |
| SCHEMBL29644723 | 0.73 | GSTP1 (0.44) | RAB9AKDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL28080906 | 0.72 | NR1H2 (0.71) | NR1H2NR1H3CMA1GSK3AGSK3B | |
| SCHEMBL4689082 | 0.72 | NR1H2 (0.78) | NR1H2NR1H3GSK3BMEN1MAPT | |
| SCHEMBL28080953 | 0.71 | TUBB4A (0.51) | NR1H2NR1H3MEN1MAPTKMT2A | |
| SCHEMBL10424199 | 0.71 | ME2 (0.69) | PTGS2ME2ME1ME3RAB9A | |
| SCHEMBL28276379 | 0.70 | PTGS2 (0.62) | PTGS2NR1H2NR1H3ME2ME1 | |
| SCHEMBL10050137 | 0.70 | NR1H2 (0.47) | PTGS2NR1H2NR1H3ME2ME1 | |
| SCHEMBL31424883 | 0.70 | PTGS2 (0.54) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456100-A | Method for preparing maleimide through cyclization of aryl acetaldehyde and primary amine | 长沙资材科技有限公司 | 2022-05-10 | — | — | CN | disclosed |