Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610103 | 0.81 | CYP3A4 (0.61) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL25179537 | 0.80 | TBXAS1 (0.62) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL770890 | 0.79 | TAAR1 (0.73) | TAAR1HDAC2HDAC8HDAC6GAA | |
| SCHEMBL4462447 | 0.79 | RECQL (0.54) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12831688 | 0.79 | HDAC2 (0.49) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL4462450 | 0.79 | HDAC8 (0.56) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3394144 | 0.79 | CYP1A2 (0.51) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12313357 | 0.79 | HDAC2 (0.56) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15178383 | 0.78 | MAPT (0.61) | SMN1; SMN2KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25784651 | 0.78 | HDAC2 (0.61) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135547-A1 | HETEROCYCLIC LOW-MOLECULAR SAPP MIMETICS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING AND USING SAME | NENAYDENOV VALENTIN G (RU) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135547-A1 | HETEROCYCLIC LOW-MOLECULAR SAPP MIMETICS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING AND USING SAME | APP, IAPP, BDNF | SMN1; SMN2 95/4885RAB9A 2368/4885MEN1 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.