Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.59 |
| ▸ | RAB9A | P51151 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.59 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 10/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644889 | 0.84 | MAPT (0.56) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644899 | 0.81 | PTPN1 (0.61) | — | |
| SCHEMBL14606092 | 0.81 | ALOX5 (0.54) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644888 | 0.81 | RAB9A (0.51) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644901 | 0.80 | XDH (0.62) | — | |
| SCHEMBL29644893 | 0.79 | PLK1 (0.52) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644884 | 0.79 | TRPV1 (0.61) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644903 | 0.78 | KDM4E (0.63) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644890 | 0.78 | PTPN1 (0.59) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL29644900 | 0.78 | PTPN1 (0.59) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |