Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 11/20 | 0.51 |
| ▸ | MMP2 | P08253 | 11/20 | 0.51 |
| ▸ | MMP9 | P14780 | 11/20 | 0.51 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644899 | 0.90 | PTPN1 (0.61) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL29644890 | 0.89 | PTPN1 (0.59) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644900 | 0.89 | PTPN1 (0.59) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644884 | 0.87 | TRPV1 (0.61) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644901 | 0.86 | XDH (0.62) | MMP1MMP2MMP9PTPN1CA12 | |
| SCHEMBL29644885 | 0.84 | MEN1 (0.59) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644903 | 0.84 | KDM4E (0.63) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644893 | 0.83 | PLK1 (0.52) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644888 | 0.83 | RAB9A (0.51) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29644902 | 0.81 | KDM1A (0.61) | MAPTMEN1KMT2APOLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |