SCHEMBL29645227

SCHEMBL29645227

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.53
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 1/20 0.45
LAP3 P28838 3/20 0.44
FOLH1 Q04609 2/20 0.43
NMT2 O60551 1/20 0.42
NMT1 P30419 1/20 0.42
GRN P28799 1/20 0.42
SORT1 Q99523 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29645226 1.00 MME (0.53) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL31289517 0.94 MME (0.48) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL29816034 0.94 MME (0.56) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL30586938 0.94 MME (0.56) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL30586939 0.94 MME (0.56) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL29624868 0.93 MME (0.56) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL30974405 0.93 MME (0.48) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL9576054 0.92 ALDH1A1 (0.55) MMEALDH1A1MEN1LMNAKMT2A
SCHEMBL30381819 0.91 FOLH1 (0.56) MMEALDH1A1FOLH1NMT2NMT1
SCHEMBL29886740 0.91 MME (0.45) MMEALDH1A1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 US disclosed
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2026-02-19 US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 US disclosed
US-20250339504-A1 CANCER VACCINE WITH USE OF COMMON CANCER ANTIGEN COCKTAIL, TCR/CAR-T CELL THERAPEUTIC, COMPANION DIAGNOSTIC METHOD, AND METHOD FOR DIAGNOSING RISK OF CANCER ONSET BY DETECTING CIRCULATING TUMOR CELLS NATIONAL CANCER CENTER (JP) 2025-11-06 US disclosed
EP-4608437-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 EP disclosed
EP-4608455-A1 SELF-ASSEMBLING NANOPARTICLES Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 EP disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 US disclosed
US-12290569-B2 Methods and compositions using peptides and proteins with c-terminal elements Sanford Burnham Prebys Medical Discovery Institute (US) 2025-05-06 US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 US disclosed
CN-111602822-B Liver fat synthesis inhibitor 不二制油集团控股株式会社 2024-10-01 CN disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 US disclosed
WO-2024097310-A2 TARGETED NON-CHARGED-NUCLEIC ACID (NCNA) DELIVERY AND RELATED TUMOR PENETRATING NANOCOMPLEXES IMPILO THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed
WO-2024092028-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 WO disclosed
WO-2024092030-A1 SELF-ASSEMBLING NANOPARTICLES VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 WO disclosed
EP-4294431-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES Vaccitech North America, Inc. (US) 2023-12-27 EP disclosed
CN-117257980-A Method, system and application for packaging and delivering exogenous protein by using heat-resistant nano caged protein particles 东沃同泰(凤城)生物工程有限公司 2023-12-22 CN disclosed
US-11628202-B2 Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia NYMOX CORPORATION (CA) 2023-04-18 US disclosed
WO-2022177993-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES VACCITECH NORTH AMERICA, INC. (US) 2022-08-25 WO disclosed
US-20220175941-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 MME 1318/4885ALDH1A1 4064/4885MEN1 449/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 MME 1690/4885ALDH1A1 1531/4885MEN1 1233/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS MME 4591/4885ALDH1A1 3087/4885MEN1 3778/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 MME 1765/4885ALDH1A1 1530/4885MEN1 1283/4885
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS CMKLR2, CRKL, CMKLR1 MME 2437/4885ALDH1A1 4873/4885MEN1 2153/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B MME 111/4885ALDH1A1 4817/4885MEN1 992/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 MME 987/4885ALDH1A1 4875/4885MEN1 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.