Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645810 | 0.90 | ADORA3 (0.35) | ADORA3ADORA2AADORA1METALK | |
| SCHEMBL29645835 | 0.86 | ADORA3 (0.39) | ADORA3ADORA2AADORA1METALK | |
| SCHEMBL29645824 | 0.84 | ADORA3 (0.39) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29645782 | 0.84 | MAPT (0.43) | ADORA3ADORA2AADORA1ALK | |
| SCHEMBL29646046 | 0.83 | ADORA1 (0.36) | ADORA3ADORA2AADORA1METAXL | |
| SCHEMBL29645475 | 0.83 | KDM4E (0.44) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29645783 | 0.83 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL29645883 | 0.82 | AMY1A (0.37) | — | |
| SCHEMBL31149921 | 0.82 | ADORA3 (0.35) | ADORA3ADORA2AADORA1MET | |
| SCHEMBL29645614 | 0.82 | TTK (0.39) | ADORA3ADORA2AADORA1AXLBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |