Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645782 | 0.89 | MAPT (0.43) | ADORA3ADORA2AALKADORA1RAD52 | |
| SCHEMBL29645919 | 0.88 | MAPT (0.41) | ADORA3AURKBMAPTALDH1A1RXFP1 | |
| SCHEMBL29645664 | 0.87 | ADORA3 (0.40) | ADORA3ADORA2AALKADORA1AURKB | |
| SCHEMBL29645548 | 0.86 | ADORA3 (0.37) | ADORA3ADORA2AALKAXLADORA1 | |
| SCHEMBL29646322 | 0.85 | RXFP1 (0.40) | ADORA3ADORA2AALKADORA1MAPT | |
| SCHEMBL29645783 | 0.84 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL29645874 | 0.84 | ADORA3 (0.40) | ADORA3ADORA2AALKADORA1MAPT | |
| SCHEMBL29645995 | 0.83 | MAPT (0.47) | ADORA3ADORA2AMAPTALDH1A1RXFP1 | |
| SCHEMBL29645501 | 0.83 | EGFR (0.33) | ADORA3ALKEGFRMETJUN | |
| SCHEMBL29645810 | 0.83 | ADORA3 (0.35) | ADORA3ADORA2AALKADORA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |