Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645799 | 0.92 | LMNA (0.38) | AMY1ALMNAMAPTTP53RXFP1 | |
| SCHEMBL29645824 | 0.91 | ADORA3 (0.39) | MAPTTP53 | |
| SCHEMBL29645502 | 0.86 | RXFP1 (0.41) | LMNAMAPTTP53RXFP1CSNK1D | |
| SCHEMBL29645778 | 0.85 | LMNA (0.38) | LMNAMAPTTP53RXFP1 | |
| SCHEMBL29645458 | 0.84 | MAPT (0.50) | MAPTTP53RXFP1 | |
| SCHEMBL29646148 | 0.83 | LMNA (0.39) | LMNAMAPTTP53RXFP1CSNK1D | |
| SCHEMBL29645475 | 0.83 | KDM4E (0.44) | MAPTTP53RXFP1 | |
| SCHEMBL29645787 | 0.83 | MAPT (0.38) | AMY1ALMNAMAPTTP53RXFP1 | |
| SCHEMBL29645825 | 0.83 | TP53 (0.41) | MAPTTP53RXFP1 | |
| SCHEMBL31150013 | 0.82 | MAPT (0.36) | AMY1ALMNAMAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |