Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 8/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645527 | 0.90 | MAPT (0.41) | MAPT | |
| SCHEMBL29646093 | 0.89 | MAT2A (0.38) | — | |
| SCHEMBL29645674 | 0.89 | MAPT (0.41) | TDO2IDO2MAPT | |
| SCHEMBL29645702 | 0.89 | MAPT (0.41) | MAPT | |
| SCHEMBL29645764 | 0.88 | ADORA3 (0.43) | MAPT | |
| SCHEMBL29645765 | 0.88 | MAPT (0.39) | MAPT | |
| SCHEMBL29645988 | 0.83 | MAPT (0.47) | MAPT | |
| SCHEMBL29645608 | 0.81 | MAPT (0.40) | DHODHMAPT | |
| SCHEMBL29645868 | 0.81 | MAPT (0.37) | MAPT | |
| SCHEMBL29645638 | 0.81 | MAPT (0.40) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |