Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645893 | 0.90 | MAPT (0.45) | MAPTTHRBMAPK9ADORA3RXFP1 | |
| SCHEMBL29645913 | 0.88 | CCNC (0.39) | MAPT | |
| SCHEMBL29645577 | 0.88 | MAPT (0.45) | MAPTTHRBADORA3RXFP1ADORA1 | |
| SCHEMBL29645943 | 0.87 | MAPT (0.50) | MAPTTHRBADORA3RXFP1ALDH1A1 | |
| SCHEMBL29645527 | 0.86 | MAPT (0.41) | MAPTTP53 | |
| SCHEMBL29646093 | 0.85 | MAT2A (0.38) | — | |
| SCHEMBL29645988 | 0.84 | MAPT (0.47) | MAPTTHRBADORA3RXFP1ADORA2A | |
| SCHEMBL29645672 | 0.83 | MAPT (0.46) | MAPTTHRBADORA3RXFP1TP53 | |
| SCHEMBL29646058 | 0.83 | MAPT (0.47) | MAPTTHRBRXFP1TP53HPGD | |
| SCHEMBL29646060 | 0.82 | TP53 (0.47) | MAPTTHRBADORA3RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |