Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645600 | 0.89 | PDK2 (0.32) | SLC40A1P2RX7AURKBPDK2JAK2 | |
| SCHEMBL31150076 | 0.87 | JAK2 (0.33) | SYKFLT3AURKBJAK2 | |
| SCHEMBL29645797 | 0.86 | JAK2 (0.32) | P2RX7SYKFLT3AURKBTP53 | |
| SCHEMBL29645601 | 0.86 | MAPT (0.35) | P2RX7FLT3JAK2 | |
| SCHEMBL29646040 | 0.84 | JAK2 (0.31) | P2RX7SYKFLT3AURKBTTK | |
| SCHEMBL29645878 | 0.83 | HSP90AA1 (0.35) | SLC40A1P2RX7TTK | |
| SCHEMBL29645692 | 0.83 | BRD4 (0.32) | AURKBJAK2 | |
| SCHEMBL29645717 | 0.83 | FLT3 (0.32) | SYKFLT3AURKBTTKPDK2 | |
| SCHEMBL29645480 | 0.83 | MAPT (0.42) | TP53 | |
| SCHEMBL31149922 | 0.81 | LIMK1 (0.35) | FLT3AURKBTP53JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |