Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645842 | 0.86 | MET (0.33) | ADORA3ADORA1ADORA2AALKPRKDC | |
| SCHEMBL29645875 | 0.84 | AXL (0.37) | ADORA3ADORA1ADORA2ABRD4MET | |
| SCHEMBL29646322 | 0.83 | RXFP1 (0.40) | ADORA3ADORA1ADORA2AALKTP53 | |
| SCHEMBL29645548 | 0.83 | ADORA3 (0.37) | ADORA3ADORA1ADORA2ABRD4ALK | |
| SCHEMBL29646046 | 0.82 | ADORA1 (0.36) | ADORA3ADORA1ADORA2ABRD4MET | |
| SCHEMBL29645782 | 0.80 | MAPT (0.43) | ADORA3ADORA1ADORA2AALKTP53 | |
| SCHEMBL29645810 | 0.80 | ADORA3 (0.35) | ADORA3ADORA1ADORA2ABRD4ALK | |
| SCHEMBL29645874 | 0.79 | ADORA3 (0.40) | ADORA3ADORA1ADORA2AALKMET | |
| SCHEMBL29645614 | 0.79 | TTK (0.39) | ADORA3ADORA1ADORA2ABRD4TP53 | |
| SCHEMBL29645783 | 0.78 | ADORA3 (0.42) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |