Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645764 | 0.91 | ADORA3 (0.43) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645957 | 0.90 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645486 | 0.88 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AMAPTABCG2 | |
| SCHEMBL29646093 | 0.88 | MAT2A (0.38) | — | |
| SCHEMBL29645503 | 0.87 | ADORA3 (0.49) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29646053 | 0.85 | ADORA3 (0.41) | ADORA3ADORA1ADORA2A | |
| SCHEMBL29645577 | 0.85 | MAPT (0.45) | ADORA3ADORA1MAPTABCG2TP53 | |
| SCHEMBL29645485 | 0.84 | MAPT (0.44) | ADORA3ADORA1MAPTABCG2TP53 | |
| SCHEMBL29645504 | 0.83 | MAPT (0.43) | ADORA3ADORA1ADORA2AMAPTTP53 | |
| SCHEMBL29645988 | 0.83 | MAPT (0.47) | ADORA3ADORA1ADORA2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |