Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645716 | 0.97 | ADORA3 (0.32) | EGFRKDM5BADORA2AADORA2BADORA1 | |
| SCHEMBL31150019 | 0.92 | EGFR (0.34) | EGFRKDM5BADORA2AADORA2BADORA1 | |
| SCHEMBL29646030 | 0.90 | KMT2A (0.35) | KDM5BADORA2AADORA1ADORA3PIM1 | |
| SCHEMBL31150114 | 0.89 | ADORA3 (0.33) | EGFRKDM5BADORA2AADORA3HDAC1 | |
| SCHEMBL29645998 | 0.88 | MAPT (0.41) | EGFRADORA1ADORA3 | |
| SCHEMBL29645810 | 0.87 | ADORA3 (0.35) | ADORA2AADORA1ADORA3 | |
| SCHEMBL29645911 | 0.86 | CLK2 (0.33) | KDM5BPIM1 | |
| SCHEMBL29645908 | 0.86 | RIPK1 (0.33) | EGFRADORA3 | |
| SCHEMBL29645471 | 0.85 | MAPT (0.40) | EGFRADORA1ADORA3 | |
| SCHEMBL29645797 | 0.84 | JAK2 (0.32) | KDM5BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |