Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GPR39 | O43194 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645716 | 0.89 | ADORA3 (0.32) | EGFRKCNH2GRM2LRRK2TBK1 | |
| SCHEMBL29645561 | 0.87 | MAP3K5 (0.34) | PIK3CASCN9AP2RX7 | |
| SCHEMBL29645471 | 0.86 | MAPT (0.40) | EGFRADORA3 | |
| SCHEMBL29645916 | 0.86 | EGFR (0.34) | EGFRADORA3 | |
| SCHEMBL29645600 | 0.84 | PDK2 (0.32) | PDK2ADORA3P2RX7 | |
| SCHEMBL29645878 | 0.83 | HSP90AA1 (0.35) | ADORA3TTKSCN9AP2RX7 | |
| SCHEMBL29645998 | 0.83 | MAPT (0.41) | EGFRADORA3 | |
| SCHEMBL31149866 | 0.82 | DYRK3 (0.35) | CLK2ADORA3STK17APIK3CA | |
| SCHEMBL31150114 | 0.81 | ADORA3 (0.33) | EGFRTBK1ADORA3TTK | |
| SCHEMBL22980061 | 0.81 | RIPK1 (0.34) | RIPK1CYP1A2KCNH2GRM2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |