Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645723 | 0.91 | P2RX7 (0.36) | P2RX7TNKSGAA | |
| SCHEMBL29645431 | 0.90 | SLC40A1 (0.35) | P2RX7SLC40A1DYRK1A | |
| SCHEMBL29645580 | 0.89 | P2RX7 (0.36) | P2RX7MAPTGAA | |
| SCHEMBL29645564 | 0.89 | P2RX7 (0.37) | P2RX7TNKSADORA3JAK2JAK1 | |
| SCHEMBL29645715 | 0.88 | MAPT (0.39) | ADORA3MAPT | |
| SCHEMBL31150091 | 0.82 | P2RX7 (0.35) | P2RX7DYRK1A | |
| SCHEMBL29645755 | 0.82 | MAPT (0.40) | ADORA3MAPT | |
| SCHEMBL29645546 | 0.82 | MAPT (0.38) | ADORA3MAPTGAAJAK2JAK1 | |
| SCHEMBL29645469 | 0.81 | P2RX7 (0.36) | P2RX7TNKS | |
| SCHEMBL29645518 | 0.81 | C1R (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |