Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645433 | 0.90 | P2RX7 (0.33) | P2RX7THRBRXFP1ALDH1A1MAPT | |
| SCHEMBL29645960 | 0.89 | P2RX7 (0.33) | P2RX7MAPTGAA | |
| SCHEMBL29645431 | 0.89 | SLC40A1 (0.35) | P2RX7NPC1POLB | |
| SCHEMBL29645642 | 0.88 | MAPT (0.43) | P2RX7MKNK2THRBRXFP1MAPT | |
| SCHEMBL29646008 | 0.84 | KDM4E (0.47) | THRBRXFP1ALDH1A1MAPTKDM4E | |
| SCHEMBL29645723 | 0.81 | P2RX7 (0.36) | P2RX7GAA | |
| SCHEMBL29645518 | 0.80 | C1R (0.38) | THRBMAPTPOLBSMN1; SMN2 | |
| SCHEMBL22987612 | 0.80 | ENPP3 (0.39) | MKNK2THRBRXFP1ALDH1A1MAPT | |
| SCHEMBL29645564 | 0.79 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL22979251 | 0.78 | KDM4E (0.36) | THRBRXFP1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |