Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645755 | 0.87 | MAPT (0.40) | ADORA3ADORA2AMAPT | |
| SCHEMBL29645825 | 0.87 | TP53 (0.41) | ADORA3TP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL29645930 | 0.87 | POLB (0.38) | ADORA3TP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL29646008 | 0.87 | KDM4E (0.47) | ADORA3TP53SMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL29645818 | 0.86 | MAPT (0.45) | KDM1AADORA3TP53POLBKDM4E | |
| SCHEMBL29645810 | 0.82 | ADORA3 (0.35) | KDM1AADORA3TP53SMN1; SMN2RXFP1 | |
| SCHEMBL29645799 | 0.82 | LMNA (0.38) | TP53RXFP1MAPT | |
| SCHEMBL29645797 | 0.81 | JAK2 (0.32) | JAK2ADORA3TP53P2RX7ADORA2A | |
| SCHEMBL29646037 | 0.81 | KDM4E (0.45) | JAK2PTK2ADORA3TP53JAK3 | |
| SCHEMBL29645808 | 0.80 | TP53 (0.45) | ADORA3TP53SMN1; SMN2RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |