Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115556 | 1.00 | TSHR (0.53) | TSHRGAAALDH1A1TP53CA1 | |
| SCHEMBL1972984 | 0.87 | AKR1C2 (0.53) | TSHRGAADHODHALPLANO1 | |
| SCHEMBL24405532 | 0.87 | GAA (0.50) | TSHRGAAALDH1A1TP53CA1 | |
| SCHEMBL22979516 | 0.86 | TSHR (0.52) | TSHRGAAALDH1A1TP53CA1 | |
| SCHEMBL31743138 | 0.85 | MAP2 (0.50) | GAAALDH1A1ALPLANO1PNLIP | |
| SCHEMBL3922656 | 0.84 | ANO1 (0.42) | TSHRGAAALPLANO1PNLIP | |
| SCHEMBL4046170 | 0.84 | DCLRE1B (0.50) | DHODHANO1AKR1C2AKR1C1KMO | |
| SCHEMBL30843111 | 0.82 | ABL1 (0.51) | ALDH1A1ALPLANO1PNLIPCNR2 | |
| SCHEMBL11060112 | 0.82 | POLB (0.52) | POLBALPLNR4A1ANO1PNLIP | |
| SCHEMBL27699137 | 0.82 | ALDH1A1 (0.59) | TSHRGAAALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004770-A | Sulfonylurea derivative and medical application thereof | 上海森辉医药有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115836050-B | Sulfonylurea derivative and medical application thereof | 上海森辉医药有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-115869303-A | Use of sulfonylureas derivatives for treating diseases | 上海森辉医药有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115836050-A | Sulfonylurea derivative and medical application thereof | 上海森辉医药有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |