Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819775 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL16342565 | 0.87 | PTGS2 (0.45) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL19433368 | 0.87 | APP (0.43) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL16395977 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL11545227 | 0.83 | TAAR1 (0.50) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL16396000 | 0.82 | GABRG2 (0.45) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL16402118 | 0.82 | TTR (0.38) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL957126 | 0.82 | PDE3B (0.47) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL16396242 | 0.80 | FEN1 (0.44) | FEN1ALOX5APCLK1 | |
| SCHEMBL14926554 | 0.79 | TTR (0.46) | ALDH1A1TTRKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124470-B | Method for preparing sulfonamide structured kinase inhibitors | 奥瑞基尼肿瘤有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-115124470-B | Method for preparing sulfonamide structured kinase inhibitors | 奥瑞基尼肿瘤有限公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-4137487-A1 | PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR | Aurigene Discovery Technologies Limited (IN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3601262-B1 | PROCESS FOR THE PREPARATION OF A SULFONAMIDE STRUCTURED KINASE INHIBITOR | AURIGENE DISCOVERY TECH LTD (IN) | 2022-11-09 | — | — | EP | disclosed |
| US-11332460-B2 | Process for the preparation of a sulfonamide structured kinase inhibitor | ORION CORPORATION (FI) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332460-B2 | Process for the preparation of a sulfonamide structured kinase inhibitor | FGFR1, FGFR2, FGFR4 | ALDH1A1 1024/4885TTR 4052/4885KDM4E 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.