Sugi Predict

Sugi Predict / Compounds / Methyl Orange

Methyl Orange

Methyl Orange

SCHEMBL296471

CN(C)c1ccc(/N=N/c2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.69
▸ RAB9A P51151 4/20 0.69
▸ KMT2A Q03164 4/20 0.69
▸ CA12 O43570 4/20 0.69
▸ CA2 P00918 4/20 0.69
▸ CA9 Q16790 4/20 0.69
▸ POLB P06746 3/20 0.69
▸ MEN1 O00255 3/20 0.69
▸ F2 P00734 3/20 0.64
▸ PRSS1 P07477 3/20 0.64
▸ PRSS2 P07478 3/20 0.64
▸ PRSS3 P35030 3/20 0.64
▸ CYP2D6 P10635 1/20 0.61
▸ ALDH1A1 P00352 4/20 0.59
▸ TSHR P16473 3/20 0.59
▸ ALOX15 P16050 2/20 0.59
▸ MAPK1 P28482 3/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ MAPT P10636 1/20 0.56
▸ HSD17B10 Q99714 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Orange SCHEMBL296472 1.00 NPC1 (0.69) NPC1RAB9AKMT2ACA12CA2
Methyl Orange SCHEMBL16163325 1.00 NPC1 (0.69) NPC1RAB9AKMT2ACA12CA2
Methyl Orange SCHEMBL19662 0.98 NPC1 (0.67) NPC1RAB9AKMT2ACA12CA2
SCHEMBL1134428 0.88 ALDH1A1 (0.55) NPC1RAB9AKMT2ACA12CA2
SCHEMBL27333040 0.86 ALDH1A1 (0.53) NPC1RAB9AKMT2ACA12CA2
Hydrochloric Acid SCHEMBL28095718 0.86 ALDH1A1 (0.53) NPC1RAB9AKMT2ACA12CA2
SCHEMBL30364928 0.86 NPC1 (0.65) NPC1RAB9AKMT2ACA12CA2
SCHEMBL9019333 0.85 NPC1 (0.69) NPC1RAB9AKMT2ACA12CA2
SCHEMBL15631068 0.85 NPC1 (0.73) NPC1RAB9AKMT2ACA12CA2
SCHEMBL29829178 0.85 CA2 (0.51) NPC1RAB9AKMT2ACA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778023-B1 Product comprising rapamycin or particular derivatives and an NMDA or AMPA antagonist for use for the treatment of epilepsy or Huntington's Disease, and the use of rapamycin or particular derivatives for the manufacture of a medicament for the treatment of epilepsy or Huntington's Disease. WYETH CORP (US) 2003-03-12 — — EP claimed
EP-0778023-A1 Neuroprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1997-06-11 — — EP claimed
US-5618726-A DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE IDAHO RESEARCH FOUNDATION, INC. (US) 1997-04-08 — — US claimed
WO-1992017550-A1 BIODEGRADABLE AZO DYES IDAHO RESEARCH FOUNDATION, INC. (US) 1992-10-15 — — WO claimed
US-12569679-B2 Treatment delivery system WearOptimo Pty Ltd (AU) 2026-03-10 — — US disclosed
US-20250025078-A1 ELECTRODE ARRANGEMENT WearOptimo Pty Ltd (AU) 2025-01-23 — — US disclosed
WO-2024006927-A1 COMPOSITIONS, KITS, AND METHODS FOR DETECTING NUCLEIC ACIDS USING INTRA-CHANNEL MULTIPLEXING Life Technologies Corporation (US) 2024-01-04 — — WO disclosed
WO-2024006477-A1 MULTIPLEX DYE COMPOUNDS Life Technologies Corporation (US) 2024-01-04 — — WO disclosed
US-11834608-B2 Silica nanoparticles for crude oil recovery using carbon dioxide, and crude oil recovery method INPEX CORPORATION (JP) 2023-12-05 — — US disclosed
US-11834608-B2 Silica nanoparticles for crude oil recovery using carbon dioxide, and crude oil recovery method INPEX CORPORATION (JP) 2023-12-05 — — US disclosed
US-20230374372-A1 SILICA NANOPARTICLES FOR CRUDE OIL RECOVERY USING CARBON DIOXIDE, AND CRUDE OIL RECOVERY METHOD INPEX CORPORATION (JP) 2023-11-23 — — US disclosed
US-20230374372-A1 SILICA NANOPARTICLES FOR CRUDE OIL RECOVERY USING CARBON DIOXIDE, AND CRUDE OIL RECOVERY METHOD INPEX CORPORATION (JP) 2023-11-23 — — US disclosed
WO-2001053521-A2 OLIGONUCLEOTIDES IDENTIFYING FUNGICIDE RESISTANT FUNGI SYNGENTA PARTICIPATIONS AG (CH) 2001-07-26 — — WO disclosed
EP-0778023-A1 Neuroprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1997-06-11 — — EP disclosed
EP-0778023-A1 Neuroprotective agents AMERICAN HOME PRODUCTS CORPORATION (US) 1997-06-11 — — EP disclosed
US-5618726-A DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE IDAHO RESEARCH FOUNDATION, INC. (US) 1997-04-08 — — US disclosed
US-5486214-A MONO OR DISAZO DYES, LIGNIN PEROXIDASE AND VERATRYL ALCOHOL MIXTURE FOR DEGRADATION OF DYES IDAHO RESEARCH FOUNDATION, INC. (US) 1996-01-23 — — US disclosed
US-5346893-A Treatment of transplantation rejection, autoimmune diseases; antiinflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1994-09-13 — — US disclosed
WO-1993018043-A1 NOVEL RAPAMYCIN 42-SULFONATES AND 42-(N-CARBOALKOXY)SULFAMATES USEFUL AS IMMUNOSUPPRESSIVE AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-09-16 — — WO disclosed
WO-1992017550-A1 BIODEGRADABLE AZO DYES IDAHO RESEARCH FOUNDATION, INC. (US) 1992-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569679-B2 Treatment delivery system PIEZO1, DSG1, KRT18 NPC1 3293/4885RAB9A 3140/4885KMT2A 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.