Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15706373 | 0.87 | NPSR1 (0.47) | NPSR1TDP1POLBMAPTGAA | |
| SCHEMBL19193384 | 0.87 | NPSR1 (0.47) | NPSR1TDP1POLBMAPTGAA | |
| SCHEMBL29648540 | 0.86 | BIRC2 (0.52) | POLBBIRC2TAS1R3TAS1R1MME | |
| SCHEMBL13765045 | 0.81 | NPSR1 (0.50) | NPSR1TDP1POLBMAPTGAA | |
| SCHEMBL18796589 | 0.80 | KMT2A (0.51) | NPSR1TDP1POLBMAPTKMT2A | |
| SCHEMBL16538716 | 0.80 | PLA2G10 (0.49) | NPSR1TDP1POLBMAPTGAA | |
| SCHEMBL29638170 | 0.80 | ALDH1A1 (0.55) | MAPTKMT2AMEN1ALDH1A1MME | |
| SCHEMBL21675512 | 0.78 | CTSK (0.61) | NPSR1TDP1POLBMAPTGAA | |
| SCHEMBL27927721 | 0.77 | FOLH1 (0.49) | POLBKMT2ABIRC2TAS1R3TAS1R1 | |
| SCHEMBL23332641 | 0.77 | CTSL (0.50) | NPSR1TDP1POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4589059-A2 | PROCESS FOR MICROSATELLITE INSTABILITY DETECTION | Personal Genome Diagnostics, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-3717520-B1 | PROCESS FOR MICROSATELLITE INSTABILITY DETECTION | PERSONAL GENOME DIAGNOSTICS INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240124889-A1 | COMPOSITIONS AND METHODS FOR THE VECTORED AUGMENTATION OF PROTEIN DESTRUCTION, EXPRESSION AND/OR REGULATION | VOYAGER THERAPEUTICS, INC. | 2024-04-18 | — | — | US | disclosed |
| US-20230160002-A1 | Process for Microsatellite Instability Detection | Personal Genome Diagnostics Inc. (US) | 2023-05-25 | — | — | US | disclosed |
| US-11597967-B2 | Process for microsatellite instability detection | Personal Genome Diagnostics Inc. (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220389449-A1 | COMPOSITIONS FOR THE TREATMENT OF DISEASE | VOYAGER THERAPEUTICS, INC. | 2022-12-08 | — | — | US | disclosed |
| US-11326182-B2 | Compositions for the treatment of disease | VOYAGER THERAPEUTICS, INC. (US) | 2022-05-10 | — | — | US | disclosed |