Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633928 | 0.94 | EPHX2 (0.54) | EPHX2KDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22979384 | 0.90 | KDM4E (0.51) | EPHX2KDM4EALDH1A1CFTRCA1 | |
| SCHEMBL13784795 | 0.78 | THRB (0.59) | ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4841210 | 0.78 | THRA (0.47) | EPHX2CFTRESRRACYP1A2CYP2C9 | |
| SCHEMBL30938349 | 0.78 | KDM4E (0.59) | EPHX2KDM4ESMN1; SMN2CFTRCA1 | |
| SCHEMBL5460005 | 0.78 | MAPK10 (0.53) | EPHX2KDM4EALDH1A1CA1CA2 | |
| SCHEMBL5729973 | 0.78 | EPHX2 (0.48) | EPHX2ALDH1A1SMN1; SMN2MAPK10P2RX1 | |
| SCHEMBL8346226 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2CFTRCA1 | |
| SCHEMBL14157044 | 0.78 | RAB9A (0.57) | EPHX2KDM4EALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL1983309 | 0.78 | AKR1C3 (0.53) | EPHX2KDM4EALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |