Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922142 | 0.75 | HAVCR2 (0.50) | KDM4EGAAMCL1UPP1RECQL | |
| SCHEMBL13906254 | 0.75 | MCL1 (0.44) | KDM4EGAAMCL1UPP1ALDH1A1 | |
| SCHEMBL5370129 | 0.75 | MCL1 (0.44) | MCL1RECQLTDP1ATM | |
| SCHEMBL103159 | 0.75 | MAPT (0.49) | KDM4EGAAMCL1ALDH1A1POLB | |
| SCHEMBL11021805 | 0.73 | KDM4E (0.45) | KDM4EGAAMCL1ALDH1A1POLB | |
| SCHEMBL5794988 | 0.71 | KDM4E (0.51) | KDM4EGAAMCL1ALDH1A1POLB | |
| SCHEMBL791101 | 0.70 | — | — | |
| SCHEMBL3821760 | 0.70 | ALDH1A1 (0.41) | KDM4EGAAMCL1ALDH1A1HPGD | |
| SCHEMBL19086336 | 0.69 | ATM (0.57) | KDM4EGAAMCL1RECQLALDH1A1 | |
| SCHEMBL7975208 | 0.69 | CYP1A2 (0.46) | KDM4EGAAUPP1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045650-A | Application of UPP1 inhibitor in preparation of medicament for treating psoriasis | 上海市东方医院（同济大学附属东方医院） | 2023-11-14 | — | — | CN | claimed |
| CN-113603636-A | Preparation method of Sotoraib intermediate | 江苏弘和药物研发有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113354578-A | Synthetic method of 2-isopropyl-3-amino-4-methylpyridine | 江苏弘和药物研发有限公司 | 2021-09-07 | — | — | CN | claimed |
| EP-1326836-B1 | PROCESS FOR MAKING 3-AMINO-2-CHLORO-4-METHYLPYRIDINE | BOEHRINGER INGELHEIM CHEMICALS (US) | 2004-05-06 | — | — | EP | claimed |
| EP-1326836-A1 | PROCESS FOR MAKING 3-AMINO-2-CHLORO-4-METHYLPYRIDINE | Boehringer Ingelheim Chemicals, Inc. (US) | 2003-07-16 | — | — | EP | claimed |
| US-6399781-B1 | A KEY INTERMEDIATE IN THE PRODUCTION OF NEVIRAPINE, STARTING BY REACTING ACETYLACETALDEHYDE DIMETHYL ACETAL WITH MALONONITRILE, IN THE PRESENCE OF AN AMMONIUM SALT CATALYST | BOEHRINGER INGELHEIM CHEMICALS, INC. | 2002-06-04 | — | — | US | claimed |
| US-20020052507-A1 | Process for making 3-amino-2-chloro-4-methylpyridine | BOEHRINGER INGELHEIM CHEMICALS, INC. | 2002-05-02 | — | — | US | claimed |
| WO-2002030901-A1 | PROCESS FOR MAKING 3-AMINO-2-CHLORO-4-METHYLPYRIDINE | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2002-04-18 | — | — | WO | claimed |
| CN-117045650-B | Application of UPP1 inhibitor in preparation of medicament for treating psoriasis | 上海市东方医院（同济大学附属东方医院） | 2025-10-03 | — | — | CN | disclosed |
| US-12371428-B2 | Pyridone compounds and methods of use | EXELIXIS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20250154109-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC | 2025-05-15 | — | — | US | disclosed |
| WO-2025029890-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |
| EP-4219463-B1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN SALUBRIS PHARM CO LTD (CN) | 2025-01-15 | — | — | EP | disclosed |
| EP-4472966-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2002030901-A1 | PROCESS FOR MAKING 3-AMINO-2-CHLORO-4-METHYLPYRIDINE | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| EP-0708147-B1 | Laser marking resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5760120-A | MOLDING MATERIALS, IMPACT RESISTANCE, RUBBER REINFORCED RESIN, TITANIUM BLACK, BLACK IRON OXIDE, YELLOW IRON OXIDE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0708147-A1 | Laser marking resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| WO-1994012352-A1 | POLYMER COMPOSITION COMPRISING A POLYMER AND AT LEAST ONE RADIATION-SENSITIVE COMPONENT | DSM N.V. (NL) | 1994-06-09 | — | — | WO | disclosed |
| EP-0095152-A1 | A process for preparing nicotinonitriles and intermediates used therein | STERLING DRUG INC. (US) | 1983-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154109-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | SCN8A, TRPV1, SCNN1A | KDM4E 3364/4885GAA 1763/4885MCL1 3931/4885 |
| US-12371428-B2 | Pyridone compounds and methods of use | PDXK, PLK2, MAP4K2 | KDM4E 2816/4885GAA 2746/4885MCL1 1466/4885 |
| US-20020052507-A1 | Process for making 3-amino-2-chloro-4-methylpyridine | MTAP, TPMT, AMPD2 | KDM4E 257/4885GAA 1840/4885MCL1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.