Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296497 | 0.75 | KDM4E (0.45) | ALDH1A1HPGDGAAHSD17B10CYP1A2 | |
| SCHEMBL5232417 | 0.71 | KCNMA1 (0.35) | HAVCR2ALDH1A1HPGDAPOBEC3GGAA | |
| SCHEMBL19416818 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAALOX15HSD17B10 | |
| SCHEMBL31050110 | 0.69 | CYP1A2 (0.46) | HAVCR2ALDH1A1HPGDAPOBEC3GGAA | |
| SCHEMBL7975208 | 0.69 | CYP1A2 (0.46) | HAVCR2ALDH1A1HPGDAPOBEC3GGAA | |
| SCHEMBL480061 | 0.69 | — | — | |
| SCHEMBL14722906 | 0.68 | IMPDH2 (0.39) | HAVCR2ALDH1A1HPGDAPOBEC3GALOX15 | |
| SCHEMBL18876109 | 0.68 | TNF (0.40) | HAVCR2ALDH1A1HPGDAPOBEC3GALOX15 | |
| SCHEMBL9820043 | 0.67 | HAVCR2 (1.00) | HAVCR2ALDH1A1HPGDAPOBEC3GGAA | |
| SCHEMBL5231081 | 0.66 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940849-B1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-1915344-B1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080207447-A1 | Cyanopyridine Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1940849-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1915344-A1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007014913-A1 | CYANOPYRIDINE PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | IPO5, PIR, ACHE | HAVCR2 4631/4885ALDH1A1 2385/4885HPGD 4044/4885 |
| US-20080207447-A1 | Cyanopyridine Pesticides | CBR3, CBR1, CHRM1 | HAVCR2 3998/4885ALDH1A1 3463/4885HPGD 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.