SCHEMBL29649710

SCHEMBL29649710

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 10/20 0.50
▸ KISS1R Q969F8 2/20 0.49
▸ CALCR P30988 4/20 0.48
▸ CRHR1 P34998 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ OPRD1 P41143 1/20 0.47
▸ NMBR P28336 1/20 0.47
▸ GRPR P30550 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30662034 0.96 GLP1R (0.53) GLP1RCALCROPRD1
SCHEMBL30030378 0.95 KISS1R (0.51) GLP1RKISS1RCALCRCRHR1CRHR2
SCHEMBL30996216 0.95 KISS1R (0.51) GLP1RKISS1RCALCRCRHR1CRHR2
SCHEMBL31450045 0.95 KISS1R (0.51) GLP1RKISS1RCALCRCRHR1CRHR2
SCHEMBL30030154 0.91 OPRD1 (0.52) GLP1RKISS1ROPRD1NMBRGRPR
SCHEMBL30874946 0.91 GLP1R (0.52) GLP1RKISS1RCALCRCRHR1CRHR2
SCHEMBL30874967 0.91 GLP1R (0.52) GLP1RKISS1RCALCRCRHR1CRHR2
SCHEMBL30874972 0.87 OPRD1 (0.53) GLP1ROPRD1
SCHEMBL29521627 0.87 GLP1R (0.58) GLP1RCALCRCRHR1CRHR2OPRD1
SCHEMBL21901298 0.87 NPY4R (0.57) GLP1RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346631-A1 PEPTIDE COMPOSITIONS AND METHODS OF USE ONL THERAPEUTICS INC (US) 2025-11-13 — — US disclosed
EP-4623925-A2 PEPTIDE COMPOSITIONS AND METHODS OF USE ONL Therapeutics, Inc. (US) 2025-10-01 — — EP disclosed
US-20250099554-A1 COMPOSITIONS AND METHODS OF FAS INHIBITION ONL THERAPEUTICS INC (US) 2025-03-27 — — US disclosed
EP-4370208-A2 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL Therapeutics, Inc. (US) 2024-05-22 — — EP disclosed
US-20240156898-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL THERAPEUTICS, INC. 2024-05-16 — — US disclosed
EP-4355349-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL Therapeutics, Inc. (US) 2024-04-24 — — EP disclosed
US-11597749-B2 Peptide compositions and methods of use THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-07 — — US disclosed
WO-2023287794-A2 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL THERAPEUTICS, INC. (US) 2023-01-19 — — WO disclosed
WO-2022266127-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL THERAPEUTICS, INC. (US) 2022-12-22 — — WO disclosed
EP-3997981-A1 PEPTIDE COMPOSITIONS AND METHODS OF USE Onl Therapeutics, Inc. (US) 2022-05-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346631-A1 PEPTIDE COMPOSITIONS AND METHODS OF USE VIP, TNFSF10, IAPP GLP1R 168/4885KISS1R 2780/4885CALCR 2040/4885
US-11597749-B2 Peptide compositions and methods of use VIP, TNFSF10, IAPP GLP1R 174/4885KISS1R 2725/4885CALCR 1907/4885
US-20240156898-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES UACA, ASAH2, NFKBIA GLP1R 4130/4885KISS1R 4789/4885CALCR 3590/4885
US-20250099554-A1 COMPOSITIONS AND METHODS OF FAS INHIBITION CFB, BAX, FASN GLP1R 4870/4885KISS1R 4883/4885CALCR 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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