SCHEMBL29649899

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	11/20	0.52

▸	NPY1R	P25929	6/20	0.52

▸	NPY2R	P49146	4/20	0.52

▸	NPY5R	Q15761	4/20	0.52

▸	C5AR1	P21730	1/20	0.48

▸	NTSR2	O95665	4/20	0.46

▸	NTSR1	P30989	4/20	0.46

▸	SORT1	Q99523	2/20	0.46

▸	GLP1R	P43220	3/20	0.46

▸	AGTR2	P50052	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29649781	0.94	AGTR2 (0.51)	NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL29701259	0.90	GLP1R (0.49)	NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL9010604	0.88	AGTR1 (0.62)	C5AR1NTSR2NTSR1SORT1AGTR2
SCHEMBL29649735	0.88	AGTR1 (0.62)	C5AR1NTSR2NTSR1SORT1AGTR2
SCHEMBL9010599	0.88	AGTR1 (0.62)	C5AR1NTSR2NTSR1SORT1AGTR2
SCHEMBL8741230	0.88	C5AR1 (0.59)	C5AR1NTSR2NTSR1SORT1AGTR2
SCHEMBL29602954	0.88	C5AR1 (0.55)	C5AR1NTSR2NTSR1SORT1AGTR2
SCHEMBL31680257	0.87	C5AR1 (0.58)	NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL7972955	0.87	NPY4R (0.51)	NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL7972947	0.87	NPY4R (0.51)	NPY4RNPY1RNPY2RNPY5RC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11331368-B2	Angiotensin receptor agonists and uses thereof	MONASH UNIVERSITY (AU)	2022-05-17	—	—	US	disclosed