SCHEMBL29649781

SCHEMBL29649781

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AGTR2 P50052 3/20 0.51
▸ AGTR1 P30556 1/20 0.51
▸ NPY4R P50391 9/20 0.49
▸ NPY1R P25929 6/20 0.49
▸ NPY2R P49146 4/20 0.49
▸ NPY5R Q15761 4/20 0.49
▸ GLP1R P43220 3/20 0.49
▸ VIPR2 P41587 3/20 0.48
▸ VIPR1 P32241 3/20 0.48
▸ C5AR1 P21730 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29701259 0.96 GLP1R (0.49) AGTR2AGTR1NPY4RNPY1RNPY2R
SCHEMBL29649899 0.94 NPY4R (0.52) AGTR2NPY4RNPY1RNPY2RNPY5R
SCHEMBL30293824 0.91 GLP1R (0.40) AGTR2AGTR1NPY4RNPY1RNPY2R
SCHEMBL30331687 0.90 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RGLP1R
Angiotensin Ii SCHEMBL9013950 0.89 AGTR2 (0.69) AGTR2AGTR1C5AR1
Angiotensin Ii SCHEMBL22125774 0.89 AGTR2 (0.69) AGTR2AGTR1C5AR1
Angiotensin Ii SCHEMBL9013957 0.89 AGTR2 (0.69) AGTR2AGTR1C5AR1
Talfirastide SCHEMBL15926158 0.89 AGTR1 (0.59) AGTR2AGTR1C5AR1
SCHEMBL7052378 0.89 AGTR2 (0.65) AGTR2AGTR1C5AR1
Angiotensin Ii SCHEMBL30960106 0.88 AGTR2 (0.68) AGTR2AGTR1C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 — — US disclosed
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease Capacity Bio, Inc. (US) 2025-07-01 — — US disclosed
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. 2022-07-28 — — US disclosed
US-11331368-B2 Angiotensin receptor agonists and uses thereof MONASH UNIVERSITY (AU) 2022-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease NLN, MAVS, PINK1 AGTR2 337/4885AGTR1 242/4885NPY4R 295/4885
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE NLN, MAVS, PINK1 AGTR2 337/4885AGTR1 242/4885NPY4R 295/4885
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE MDH2, NLN, PINK1 AGTR2 1203/4885AGTR1 1006/4885NPY4R 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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