SCHEMBL2964992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6011438	0.85	CYP3A4 (0.58)	TDO2MAOBCYP3A4CYP1A1CYP1A2
	Hydrochloric Acid SCHEMBL6011564	0.83	CYP3A4 (0.56)	TDO2MAOBCYP3A4CYP1A1CYP1A2
	SCHEMBL14850870	0.83	ACHE (0.57)	ACHETDO2MAOBALKBH3CYP3A4
	SCHEMBL4925801	0.81	CYP1A1 (0.69)	ACHETDO2MAOBALKBH3CYP3A4
	SCHEMBL31507403	0.81	ACHE (0.55)	ACHETDO2MAOBALKBH3CYP3A4
	SCHEMBL2955919	0.81	CYP3A4 (0.50)	ACHEMAOBALKBH3CYP3A4CYP1A2
	SCHEMBL396757	0.81	TDO2 (0.55)	TDO2MAOBCYP3A4CYP1A1CYP1A2
	SCHEMBL30785681	0.81	TDO2 (0.55)	TDO2MAOBCYP3A4CYP1A1CYP1A2
	SCHEMBL24767284	0.80	ACHE (0.53)	ACHETDO2MAOBALKBH3CYP3A4
	SCHEMBL277912	0.79	ACHE (0.57)	ACHETDO2MAOBALKBH3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.