SCHEMBL29652155

SCHEMBL29652155

C[Si](C)(C)c1c(C(=O)O)cc(C(=O)O)cc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALOX15 P16050 1/20 0.48
HIF1A Q16665 1/20 0.48
TPMT P51580 3/20 0.44
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
HPGD P15428 2/20 0.40
KDM4E B2RXH2 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
TP53 P04637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34471921 0.80 KEAP1 (0.44) HPGDKDM4EALDH1A1HSD17B10HCAR1
SCHEMBL23631958 0.76 ALOX15 (0.46) TSHRALOX15HIF1ATPMTCA12
SCHEMBL34472984 0.74 ALDH1A1 (0.52) TSHRALOX15CA12CA1CA2
SCHEMBL16616281 0.73 CYP1A2 (0.50) TSHRALOX15CA12CA1CA2
SCHEMBL3097749 0.73 TPMT (0.56) TSHRALOX15HIF1ATPMTCA12
SCHEMBL5834636 0.72 KDM4E (0.47) TSHRTPMTCA12CA1CA2
SCHEMBL5833655 0.71 HPGD (0.48) TSHRALOX15HIF1ATPMTCA12
Fluoride SCHEMBL11641082 0.71 TPMT (0.54) TSHRALOX15HIF1ATPMTCA12
SCHEMBL2897282 0.71 HPGD (0.48) TSHRALOX15HIF1ATPMTCA12
SCHEMBL11367428 0.71 TPMT (0.48) TSHRALOX15TPMTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415817-B1 Mixed-metal metal organic framework KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-16 US disclosed
US-20250276985-A1 MIXED-METAL METAL ORGANIC FRAMEWORK KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-04 US disclosed
US-12319704-B2 Multimetal-metal organic framework adsorbent KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-06-03 US disclosed
US-20220372049-A1 MULTIMETAL-METAL ORGANIC FRAMEWORK ADSORBENT KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-11-24 US disclosed
US-11420983-B2 Molecular hydrogen adsorbent comprising copper-BTC MOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-08-23 US disclosed
US-20220144859-A1 MOLECULAR HYDROGEN ADSORBENT COMPRISING COPPER-BTC MOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-05-12 US disclosed