SCHEMBL29652358

SCHEMBL29652358

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3cccc(C4=CCCCC4)c23)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ KAT7 O95251 5/20 0.33
▸ KAT6A Q92794 5/20 0.33
▸ KAT6B Q8WYB5 4/20 0.33
▸ KAT5 Q92993 3/20 0.33
▸ KAT8 Q9H7Z6 3/20 0.33
▸ OXTR P30559 1/20 0.33
▸ MAPT P10636 4/20 0.33
▸ TP53 P04637 2/20 0.32
▸ POLB P06746 1/20 0.31
▸ RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28906748 1.00 ALDH1A1 (0.34) ALDH1A1TSHRKMT2AKAT7KAT6A
SCHEMBL28522685 0.89 ALDH1A1 (0.34) ALDH1A1TSHRKMT2AKAT7KAT6A
SCHEMBL29652560 0.89 ALDH1A1 (0.34) ALDH1A1TSHRKMT2AKAT7KAT6A
SCHEMBL29652392 0.86 KAT7 (0.38) ALDH1A1KAT7KAT6AKAT6BKAT5
SCHEMBL21596833 0.85 OXTR (0.37) ALDH1A1TSHRKAT7KAT6AKAT6B
SCHEMBL31605593 0.85 OXTR (0.37) ALDH1A1TSHRKAT7KAT6AKAT6B
SCHEMBL31605635 0.84 KDM4E (0.36) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21596863 0.84 KDM4E (0.36) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29652415 0.84 KAT7 (0.37) KMT2AKAT7KAT6AKAT6BKAT5
SCHEMBL29652370 0.79 KAT7 (0.41) KMT2AKAT7KAT6AKAT6BKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 ALDH1A1 981/4885TSHR 3584/4885KMT2A 4165/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B ALDH1A1 1864/4885TSHR 832/4885KMT2A 890/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 ALDH1A1 982/4885TSHR 3583/4885KMT2A 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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