SCHEMBL21596863

SCHEMBL21596863

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3cccc(-c4cnn(C)c4)c23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KAT7 O95251 6/20 0.36
▸ KAT6A Q92794 6/20 0.36
▸ KAT6B Q8WYB5 4/20 0.36
▸ KAT5 Q92993 3/20 0.36
▸ KAT8 Q9H7Z6 3/20 0.36
▸ CCNA2 P20248 1/20 0.36
▸ CDK2 P24941 1/20 0.36
▸ TTK P33981 1/20 0.36
▸ OXTR P30559 2/20 0.35
▸ MAPT P10636 2/20 0.33
▸ KDR P35968 2/20 0.33
▸ PTGDR2 Q9Y5Y4 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ FGFR3 P22607 1/20 0.33
▸ ALPL P05186 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.32
▸ LRRK2 Q5S007 1/20 0.32
▸ CSF1R P07333 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31605635 1.00 KDM4E (0.36) KDM4EPOLBKAT7KAT6AKAT6B
SCHEMBL21596833 0.89 OXTR (0.37) KDM4EPOLBKAT7KAT6AKAT6B
SCHEMBL31605593 0.89 OXTR (0.37) KDM4EPOLBKAT7KAT6AKAT6B
SCHEMBL21641940 0.86 MET (0.37) KDM4EPOLBKAT7KAT6AKAT6B
SCHEMBL29652527 0.86 MET (0.37) KDM4EPOLBKAT7KAT6AKAT6B
SCHEMBL29652392 0.86 KAT7 (0.38) POLBKAT7KAT6AKAT6BKAT5
SCHEMBL29652358 0.84 ALDH1A1 (0.34) POLBKAT7KAT6AKAT6BKAT5
SCHEMBL28906748 0.84 ALDH1A1 (0.34) POLBKAT7KAT6AKAT6BKAT5
SCHEMBL29652415 0.83 KAT7 (0.37) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL28512950 0.81 CCNA2 (0.36) KDM4EPOLBKAT7KAT6AKAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed
EP-3810602-A1 COMPOUNDS CTXT Pty Limited (AU) 2021-04-28 — — EP disclosed
CN-112334466-A Compound (I) CTXT私人有限公司 2021-02-05 — — CN disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 — — US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KDM4E 4009/4885POLB 3605/4885KAT7 490/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 KDM4E 4009/4885POLB 3604/4885KAT7 490/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KDM4E 800/4885POLB 4118/4885KAT7 271/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KDM4E 4009/4885POLB 3604/4885KAT7 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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