SCHEMBL29652444

SCHEMBL29652444

CCc1ccc(CON(c2noc3c(Br)cccc23)S(=O)(=O)c2cc(CC)ccc2OC)c(CC)c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.35
▸ TP53 P04637 4/20 0.35
▸ ALPL P05186 1/20 0.35
▸ KAT7 O95251 3/20 0.34
▸ KAT6B Q8WYB5 3/20 0.34
▸ KAT6A Q92794 3/20 0.34
▸ KAT5 Q92993 2/20 0.34
▸ KAT8 Q9H7Z6 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ TSHR P16473 2/20 0.34
▸ EDNRB P24530 3/20 0.33
▸ EDNRA P25101 3/20 0.33
▸ BRD4 O60885 1/20 0.31
▸ BRD2 P25440 1/20 0.31
▸ BRD3 Q15059 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516294 1.00 MAPT (0.35) MAPTTP53ALPLKAT7KAT6B
SCHEMBL21596809 0.92 MAPT (0.36) MAPTTP53ALPLKAT7KAT6B
SCHEMBL29652454 0.92 MAPT (0.36) MAPTTP53ALPLKAT7KAT6B
SCHEMBL29652522 0.80 ALDH1A1 (0.32) MAPTTP53ALPLKAT7KAT6B
SCHEMBL21596821 0.80 MAPT (0.38) MAPTALPLKAT7KAT6BKAT6A
SCHEMBL31605552 0.80 MAPT (0.38) MAPTALPLKAT7KAT6BKAT6A
SCHEMBL28906747 0.80 ALDH1A1 (0.32) MAPTTP53ALPLKAT7KAT6B
SCHEMBL29652573 0.80 MAPT (0.36) MAPTTP53ALPLKAT7KAT6B
SCHEMBL29652540 0.80 KAT7 (0.33) MAPTTP53ALPLKAT7KAT6B
SCHEMBL28507830 0.80 KAT7 (0.33) MAPTTP53ALPLKAT7KAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1135/4885TP53 3501/4885ALPL 1526/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B MAPT 2629/4885TP53 4584/4885ALPL 3469/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1136/4885TP53 3504/4885ALPL 1524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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