SCHEMBL29652573

SCHEMBL29652573

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3c(Br)cccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.36
▸ TP53 P04637 2/20 0.36
▸ KEAP1 Q14145 1/20 0.35
▸ NFE2L2 Q16236 1/20 0.35
▸ ALPL P05186 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ KAT7 O95251 2/20 0.34
▸ KAT6B Q8WYB5 2/20 0.34
▸ KAT6A Q92794 2/20 0.34
▸ POLB P06746 2/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ OXTR P30559 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ KAT5 Q92993 1/20 0.33
▸ KAT8 Q9H7Z6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652454 0.87 MAPT (0.36) MAPTTP53ALPLKAT7KAT6B
SCHEMBL21596809 0.87 MAPT (0.36) MAPTTP53ALPLKAT7KAT6B
SCHEMBL29652370 0.85 KAT7 (0.41) MAPTTP53KAT7KAT6BKAT6A
SCHEMBL21596810 0.84 TSHR (0.39) MAPTTP53KAT7KAT6BKAT6A
SCHEMBL29652373 0.84 TSHR (0.39) MAPTTP53KAT7KAT6BKAT6A
SCHEMBL30838424 0.84 TSHR (0.39) MAPTTP53KAT7KAT6BKAT6A
SCHEMBL29652560 0.84 ALDH1A1 (0.34) MAPTTP53ALPLTDP1KAT7
SCHEMBL28522685 0.84 ALDH1A1 (0.34) MAPTTP53ALPLTDP1KAT7
SCHEMBL29652392 0.82 KAT7 (0.38) MAPTTP53ALPLTDP1KAT7
SCHEMBL21596794 0.82 MAPT (0.37) MAPTTP53KAT7KAT6BKAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1135/4885TP53 3501/4885KEAP1 824/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B MAPT 2629/4885TP53 4584/4885KEAP1 4171/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1136/4885TP53 3504/4885KEAP1 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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