Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297463 | 0.86 | PDE4B (0.50) | ALDH1A1TSHRPDE4BPDE4DTRPV1 | |
| SCHEMBL5237997 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHR | |
| SCHEMBL2543314 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRPDE4BPDE4DTRPV1 | |
| SCHEMBL34467742 | 0.80 | PDE4B (0.43) | ALDH1A1TSHRPDE4BPDE4DTRPV1 | |
| SCHEMBL23672389 | 0.78 | PDE4B (0.55) | PDE4BPDE4D | |
| SCHEMBL298304 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRPDE4BPDE4DKDM4E | |
| SCHEMBL30636796 | 0.75 | PDE4B (0.47) | PDE4BPDE4D | |
| SCHEMBL31124568 | 0.75 | HTT (0.48) | ALDH1A1TSHRKDM4E | |
| SCHEMBL297279 | 0.74 | MAPT (0.49) | ALDH1A1PDE4BPDE4DTRPV1 | |
| SCHEMBL9615234 | 0.74 | CDK4 (0.45) | ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-2106401-B1 | DERIVATIVES OF PYRROLOPYRIDINE-2-CARBOXAMIDS, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |