Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296528 | 0.86 | ALDH1A1 (0.47) | PDE4BALDH1A1TSHRPDE4DTRPV1 | |
| SCHEMBL23672389 | 0.81 | PDE4B (0.55) | PDE4BPDE4D | |
| SCHEMBL2537807 | 0.80 | PDE4B (0.44) | PDE4BALDH1A1TSHRPDE4DMEN1 | |
| SCHEMBL34467742 | 0.80 | PDE4B (0.43) | PDE4BALDH1A1TSHRPDE4DTRPV1 | |
| SCHEMBL298304 | 0.79 | ALDH1A1 (0.45) | PDE4BALDH1A1TSHRPDE4DMEN1 | |
| SCHEMBL30636798 | 0.77 | PDE4B (0.41) | PDE4BPDE4D | |
| SCHEMBL4411023 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRMEN1POLBPABPC1 | |
| SCHEMBL298062 | 0.76 | CCR2 (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3758947 | 0.75 | MCL1 (0.56) | PDE4BALDH1A1MEN1POLBKMT2A | |
| SCHEMBL30226404 | 0.75 | PARP1 (0.45) | PDE4BALDH1A1TSHRPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106401-B1 | DERIVATIVES OF PYRROLOPYRIDINE-2-CARBOXAMIDS, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |