Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668215 | 0.87 | PLA2G10 (0.61) | ALDH1A1TSHRPLA2G10IDO1CCR2 | |
| SCHEMBL30194196 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL5208338 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL29834867 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRPLA2G10IDO1MAPT | |
| SCHEMBL296528 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL11004197 | 0.81 | NOD2 (0.50) | ALDH1A1TSHRIDO1MAPTGSR | |
| SCHEMBL12091859 | 0.79 | HAO1 (0.50) | ALDH1A1TSHRPLA2G10APPGAA | |
| SCHEMBL12094440 | 0.79 | RECQL (0.47) | ALDH1A1TSHRPLA2G10IDO1ALOX12 | |
| Dimethylamine SCHEMBL4930574 | 0.79 | ALDH1A1 (0.87) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL12091860 | 0.77 | KMO (0.54) | ALDH1A1TSHRPLA2G10APPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765775-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123675-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |