Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | MPL | P40238 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474291 | 0.92 | LTA4H (0.82) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL21479710 | 0.85 | KDM4E (0.68) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL28708805 | 0.84 | LTA4H (0.62) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL29654146 | 0.84 | LTA4H (0.51) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL29653953 | 0.82 | ALDH1A1 (0.83) | LTA4HKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29654121 | 0.81 | RAB9A (0.55) | LTA4HKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21462074 | 0.79 | KDM4E (0.68) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL21462073 | 0.79 | KDM4E (0.61) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL28355353 | 0.79 | KDM4E (0.68) | LTA4HKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL15160564 | 0.78 | KDM4E (0.71) | LTA4HKDM4EMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |