SCHEMBL29655244

SCHEMBL29655244

O=c1[nH]ncc2cc(F)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
PARP1 P09874 2/20 0.56
PRKCI P41743 1/20 0.56
PDE4B Q07343 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
DAO P14920 2/20 0.43
TYMS P04818 1/20 0.42
METAP2 P50579 1/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 2/20 0.38
SGK1 O00141 1/20 0.38
CTNNB1 P35222 1/20 0.38
WNT3A P56704 1/20 0.38
MET P08581 2/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15577321 1.00 ALDH1A1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL21917350 0.85 PARP1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL29390884 0.85 PARP1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL31331121 0.78 PARP1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL396016 0.78 METAP2 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL25184048 0.78 ALDH1A1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL29735151 0.78 METAP2 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL1008698 0.78 ALDH1A1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL4060395 0.78 PARP1 (0.61) ALDH1A1PARP1PRKCIPDE4BHSD17B10
SCHEMBL30375696 0.78 ALDH1A1 (0.56) ALDH1A1PARP1PRKCIPDE4BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4640686-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Innocure Therapeutics, Inc. (KR) 2025-10-29 EP disclosed
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
CN-109843874-B Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer 加利福尼亚大学董事会 2022-05-27 CN disclosed