Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.56 |
| ▸ | NOS1 | P29475 | 3/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29735151 | 1.00 | METAP2 (0.56) | METAP2NOS1CSNK2A1ALDH1A1PARP1 | |
| SCHEMBL392303 | 0.85 | METAP2 (0.56) | METAP2NOS1CSNK2A1ALDH1A1PARP1 | |
| SCHEMBL29599162 | 0.85 | METAP2 (0.56) | METAP2NOS1CSNK2A1ALDH1A1PARP1 | |
| SCHEMBL30375696 | 0.78 | ALDH1A1 (0.56) | METAP2NOS1CSNK2A1ALDH1A1PARP1 | |
| SCHEMBL31331121 | 0.78 | PARP1 (0.56) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL25184048 | 0.78 | ALDH1A1 (0.56) | METAP2NOS1CSNK2A1ALDH1A1PARP1 | |
| SCHEMBL29655244 | 0.78 | ALDH1A1 (0.56) | METAP2ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL4060395 | 0.78 | PARP1 (0.61) | CSNK2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL1008698 | 0.78 | ALDH1A1 (0.56) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL15577321 | 0.78 | ALDH1A1 (0.56) | METAP2ALDH1A1PARP1PRKCIPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772595-A | Wear-resistant glass fiber reinforced plastic well lid containing polyester and preparation method thereof | 山东金光复合材料股份有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-4207112-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-06-10 | — | — | US | claimed |
| US-4096143-A | Process for producing phthalazinone and derivatives of the same | FUJI PHOTO FILM CO., LTD. (JA) | 1978-06-20 | — | — | US | claimed |
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | SITRYX THERAPEUTICS LIMITED (GB) | 2026-03-26 | — | — | US | disclosed |
| US-20260070932-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260035354-A1 | PIPERIDINEDIONE DERIVATIVES | INNOCURE THERAPEUTICS, INC. (KR) | 2026-02-05 | — | — | US | disclosed |
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12509474-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-1999038850-A1 | NOVEL ALKANOIC ACIDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-08-05 | — | — | WO | disclosed |
| EP-0309765-A2 | 1(2H)-Phthalazinones as cytoprotective agents | FISONS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4769369-A | Anti-allergy 1(2H)-phthalazinones | PENNWALT CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |
| US-4237215-A | DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4207112-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |
| US-4144072-A | CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-03-13 | — | — | US | disclosed |
| US-4125403-A | ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE | FUJI PHOTO FILM CO., LTD. | 1978-11-14 | — | — | US | disclosed |
| US-4096143-A | Process for producing phthalazinone and derivatives of the same | FUJI PHOTO FILM CO., LTD. (JA) | 1978-06-20 | — | — | US | disclosed |
| US-4076534-A | Heat developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | PDK1, PDK2, PDK4 | METAP2 3415/4885NOS1 2966/4885CSNK2A1 190/4885 |
| US-20260035354-A1 | PIPERIDINEDIONE DERIVATIVES | CRBN, PSMC1, PSME3 | METAP2 2929/4885NOS1 1343/4885CSNK2A1 86/4885 |
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | EGFR, ERBB3, ERBB2 | METAP2 3008/4885NOS1 4288/4885CSNK2A1 228/4885 |
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | METAP2 4076/4885NOS1 1762/4885CSNK2A1 701/4885 |
| US-12509474-B2 | Inhibitors of complement factors and uses thereof | SSB, UACA, CFH | METAP2 1806/4885NOS1 2090/4885CSNK2A1 885/4885 |
| US-20260070932-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFH, CFB, C5 | METAP2 717/4885NOS1 879/4885CSNK2A1 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.