Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 10/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CTSK | P43235 | 3/20 | 0.62 |
| ▸ | GLP1R | P43220 | 4/20 | 0.61 |
| ▸ | GCGR | P47871 | 4/20 | 0.61 |
| ▸ | GIPR | P48546 | 1/20 | 0.61 |
| ▸ | CTSH | P09668 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655839 | 0.93 | CXCR4 (0.63) | CXCR4KEAP1C5AR1CTSLCTSS | |
| SCHEMBL30567718 | 0.90 | KEAP1 (0.68) | KEAP1C5AR1GLP1RGCGRGIPR | |
| SCHEMBL30607317 | 0.90 | KEAP1 (0.67) | CXCR4KEAP1C5AR1GLP1RGCGR | |
| SCHEMBL31307904 | 0.90 | CXCR4 (0.68) | CXCR4KEAP1CTSLCTSSCTSK | |
| SCHEMBL30712896 | 0.90 | C5AR1 (0.63) | CXCR4KEAP1C5AR1GLP1RGCGR | |
| SCHEMBL30429341 | 0.89 | GLP1R (0.68) | CXCR4KEAP1C5AR1GLP1RGCGR | |
| SCHEMBL30432159 | 0.88 | C5AR1 (0.73) | CXCR4KEAP1C5AR1GLP1RGCGR | |
| SCHEMBL29949915 | 0.87 | KEAP1 (0.69) | CXCR4KEAP1GLP1RGCGRGIPR | |
| SCHEMBL31148810 | 0.87 | GLP1R (0.68) | CXCR4KEAP1C5AR1GLP1RGCGR | |
| SCHEMBL29697166 | 0.87 | CTSL (0.62) | CXCR4KEAP1C5AR1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | claimed |
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | CYP24A1, CYP27B1, CYP2R1 | CXCR4 1077/4885KEAP1 2064/4885C5AR1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.