Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 10/20 | 0.50 |
| ▸ | GRPR | P30550 | 3/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655864 | 0.97 | PRMT1 (0.52) | GLP1RGRPRPRMT1OPRM1OPRD1 | |
| SCHEMBL38660507 | 0.85 | GRPR (0.58) | GLP1RGRPROPRM1OPRD1NPBWR1 | |
| SCHEMBL29742991 | 0.84 | EDNRA (0.54) | GLP1RGRPRPRMT1OPRM1OPRD1 | |
| SCHEMBL31256996 | 0.84 | ERAP2 (0.62) | ERAP2 | |
| SCHEMBL31223150 | 0.84 | GRPR (0.61) | GLP1RGRPROPRM1OPRD1 | |
| SCHEMBL30950657 | 0.84 | OPRM1 (0.58) | GRPRPRMT1OPRM1OPRD1NPBWR1 | |
| SCHEMBL29973230 | 0.84 | IL23R (0.55) | GLP1RGRPRKEAP1NPBWR1 | |
| SCHEMBL29430203 | 0.84 | GLP1R (0.61) | GLP1R | |
| SCHEMBL29497517 | 0.83 | GRPR (0.57) | GLP1RGRPRKEAP1 | |
| SCHEMBL20764506 | 0.83 | GRPR (0.59) | GLP1RGRPROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | claimed |
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | CYP24A1, CYP27B1, CYP2R1 | GLP1R 3593/4885GRPR 1381/4885PRMT1 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.