Sugi Predict

Sugi Predict / Compounds / SCHEMBL29657968

SCHEMBL29657968

SCHEMBL29657968

c1ccc2[nH]c(N=Nc3cc4ccccc4[nH]3)cc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 2/20 0.52
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ LOXL2 Q9Y4K0 1/20 0.47
▸ FLT3 P36888 1/20 0.47
▸ CYP2A6 P11509 1/20 0.47
▸ KDM4E B2RXH2 4/20 0.45
▸ MAPT P10636 3/20 0.45
▸ DAO P14920 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ SRD5A2 P31213 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ BRD4 O60885 1/20 0.45
▸ DDO Q99489 1/20 0.45
▸ CA2 P00918 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.42
▸ CHEK1 O14757 1/20 0.42
▸ KDR P35968 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11500406 0.98 NPC1 (0.52) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL6249932 0.90 ALDH1A1 (0.46) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL1002265 0.87 AOC3 (0.45) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL1002262 0.87 AOC3 (0.45) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL5173283 0.87 FLT3 (0.46) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL6654107 0.86 AOC3 (0.52) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL11356701 0.85 IDO1 (0.42) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL2775635 0.82 FLT3 (0.48) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL5598773 0.82 AOC3 (0.48) AOC3NPC1RAB9ALOXL2FLT3
SCHEMBL3900366 0.81 AOC3 (0.37) AOC3NPC1RAB9ALOXL2FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688750-A1 SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF AS AMPK ACTIVATORS Pfizer Inc. (US) 2026-02-11 — — EP disclosed
US-20260002940-A1 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS ABRUS BIO INC (US) 2026-01-01 — — US disclosed
US-12474347-B2 Determination of protein information by recoding amino acid polymers into DNA polymers ABRUS BIO, INC. (US) 2025-11-18 — — US disclosed
WO-2025151826-A1 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS WITH METADATA TAGGING ABRUS BIO, INC. (US) 2025-07-17 — — WO disclosed
EP-4573372-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-06-25 — — EP disclosed
CN-120136765-A Synthesis method of N-protected 2-benzoyl-3-aryl azo indole 新疆大学 2025-06-13 — — CN disclosed
EP-4555134-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-05-21 — — EP disclosed
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 — — US disclosed
US-12291523-B2 LXR modulators with bicyclic core moiety ORSOBIO, INC. (US) 2025-05-06 — — US disclosed
CN-119790193-A Determination of protein information by recoding amino acid polymers into DNA polymers 阿布鲁斯生物公司 2025-04-08 — — CN disclosed
EP-3814331-B9 NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY ORSOBIO INC (US) 2023-08-09 — — EP disclosed
CN-116283712-A (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides 优时比制药有限公司 2023-06-23 — — CN disclosed
EP-3814331-B1 NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY ORSOBIO INC (US) 2023-06-14 — — EP disclosed
US-11661423-B2 Heterocyclic compounds as RET kinase inhibitors CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-05-30 — — US disclosed
CN-116036078-A (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides 优时比制药有限公司 2023-05-02 — — CN disclosed
US-11618747-B2 LXR modulators with bicyclic core moiety ORSOBIO, INC. (US) 2023-04-04 — — US disclosed
EP-4104837-A2 HETEROCYCLIC COMPOUNDS AS RET KINASE INHIBITORS Cancer Research Technology Limited (GB) 2022-12-21 — — EP disclosed
US-20220227729-A1 IDENTIFICATION AND USE OF KRAS INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 — — US disclosed
EP-3442535-B1 HETEROCYCLIC COMPOUNDS AS RET KINASE INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-06-01 — — EP disclosed
EP-3972963-A1 IDENTIFICATION AND USE OF KRAS INHIBITORS Bayer Aktiengesellschaft (DE) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661423-B2 Heterocyclic compounds as RET kinase inhibitors RET, HIPK4, HIPK3 AOC3 2296/4885NPC1 4056/4885RAB9A 1500/4885
US-11618747-B2 LXR modulators with bicyclic core moiety NR1H2, NR1H3, NR1H4 AOC3 4388/4885NPC1 260/4885RAB9A 3581/4885
US-20220227729-A1 IDENTIFICATION AND USE OF KRAS INHIBITORS KRAS, NRAS, BRCA1 AOC3 4500/4885NPC1 2089/4885RAB9A 73/4885
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS KRAS, NRAS, TP53 AOC3 4212/4885NPC1 3060/4885RAB9A 103/4885
US-20260002940-A1 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS DNMT3A, PCNA, MAX AOC3 3317/4885NPC1 4485/4885RAB9A 3024/4885
US-12291523-B2 LXR modulators with bicyclic core moiety NR1H2, NR1H3, NR1H4 AOC3 3645/4885NPC1 321/4885RAB9A 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.