Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.52 |
| ▸ | GHSR | Q92847 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | NMBR | P28336 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051166 | 0.92 | OPRM1 (0.64) | OPRM1OPRD1GHSRNMBRKDM4E | |
| SCHEMBL29842333 | 0.91 | KDM4E (0.56) | OPRM1OPRD1PRMT1ACEKDM4E | |
| SCHEMBL29551274 | 0.90 | GHSR (0.60) | KISS1RGHSRIL23R | |
| SCHEMBL30169323 | 0.90 | OPRM1 (0.62) | OPRM1OPRD1GHSRKDM4EMEN1 | |
| SCHEMBL30834731 | 0.88 | ACE (0.53) | OPRM1OPRD1MMP2MMP9MMP8 | |
| SCHEMBL29564909 | 0.88 | OPRM1 (0.63) | OPRM1OPRD1GHSR | |
| SCHEMBL30051966 | 0.88 | OPRM1 (0.65) | OPRM1OPRD1NMBR | |
| SCHEMBL30665628 | 0.88 | KISS1R (0.55) | OPRM1OPRD1KISS1RGHSRPRMT1 | |
| SCHEMBL30052868 | 0.87 | KDM4E (0.60) | OPRM1OPRD1MMP2MMP9MMP8 | |
| SCHEMBL30123108 | 0.86 | OPRD1 (0.54) | OPRM1OPRD1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478789-A | anti-PD-L1 and OX40 bispecific antibodies and uses thereof | 安徽安科生物工程（集团）股份有限公司 | 2022-05-13 | — | — | CN | disclosed |