Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408003 | 0.91 | DPP4 (0.45) | DPP4DPP8FAPDPP9DPP7 | |
| SCHEMBL29397226 | 0.90 | DPP4 (0.44) | CAPN1GRB2DPP4DPP8FAP | |
| SCHEMBL30159321 | 0.90 | CAPN1 (0.43) | CAPN1CTSBREN | |
| SCHEMBL29397117 | 0.88 | DPP4 (0.46) | CAPN1DPP4DPP8FAPDPP9 | |
| SCHEMBL29658176 | 0.86 | GRB2 (0.44) | CAPN1GRB2RENNTSR2 | |
| SCHEMBL30066756 | 0.86 | NTSR2 (0.46) | CAPN1RENNTSR2 | |
| SCHEMBL31140016 | 0.85 | CAPN1 (0.41) | CAPN1GRB2REN | |
| SCHEMBL29669249 | 0.84 | REN (0.45) | GRB2RENNTSR2 | |
| SCHEMBL31399255 | 0.83 | REN (0.44) | GRB2RENNTSR2 | |
| SCHEMBL30395175 | 0.83 | REN (0.39) | CAPN1CTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478744-A | Long-acting GLP-1 antagonist | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |