Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 10/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669249 | 0.98 | REN (0.45) | GRB2RENOPRM1NTSR2F2 | |
| SCHEMBL31399255 | 0.97 | REN (0.44) | GRB2RENOPRM1NTSR2F2 | |
| SCHEMBL30937369 | 0.94 | REN (0.43) | GRB2RENOPRM1NTSR2F2 | |
| SCHEMBL29962469 | 0.92 | REN (0.44) | RENOPRM1NTSR2F2 | |
| SCHEMBL30028306 | 0.89 | OPRM1 (0.46) | GRB2RENOPRM1NTSR2F2 | |
| SCHEMBL29468849 | 0.88 | REN (0.45) | GRB2RENNTSR2F2NTSR1 | |
| SCHEMBL29801925 | 0.88 | REN (0.45) | GRB2RENNTSR2F2NTSR1 | |
| SCHEMBL29350551 | 0.86 | GRB2 (0.56) | GRB2NTSR2F2NTSR1 | |
| SCHEMBL29658175 | 0.86 | CAPN1 (0.42) | GRB2RENNTSR2CAPN1 | |
| SCHEMBL29397226 | 0.86 | DPP4 (0.44) | GRB2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478744-A | Long-acting GLP-1 antagonist | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |