SCHEMBL29658282

SCHEMBL29658282

CCc1ccc(C(=O)O)c(C(=O)O)c1CC.COC(=O)c1ccccc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 6/20 0.42
HTT P42858 1/20 0.42
CFTR P13569 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CLCN2 P51788 2/20 0.41
ALOX15 P16050 2/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
CDC25B P30305 1/20 0.40
GAA P10253 1/20 0.40
MYC P01106 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL29429444 0.91 ALDH1A1 (0.48) LMNAALDH1A1HTTHSD17B10CLCN2
Phthalic Acid SCHEMBL10963447 0.91 ALDH1A1 (0.48) LMNAALDH1A1HTTHSD17B10CLCN2
Methyl Benzoate SCHEMBL30655827 0.89 TSHR (0.54) LMNATSHRALDH1A1CLCN2MAPT
Diethyl Phthalate SCHEMBL30147367 0.86 TSHR (0.60) LMNATSHRALDH1A1HTTHSD17B10
Diethyl Phthalate SCHEMBL8873370 0.86 TSHR (0.60) LMNATSHRALDH1A1HTTHSD17B10
SCHEMBL75798 0.84 ALDH1A1 (0.41) TSHRALDH1A1CLCN2ALOX15MAPT
SCHEMBL17911667 0.83 GABRP (0.40) TSHRALDH1A1CLCN2ALOX15MAPT
Toluic Acid SCHEMBL11277682 0.82 CYP3A4 (0.43) TSHRALDH1A1HTTHSD17B10CLCN2
Acetic Acid SCHEMBL10946506 0.81 GABRP (0.39) TSHRALDH1A1HSD17B10CLCN2ALOX15
Dibutyl Phthalate SCHEMBL29658281 0.81 TSHR (0.64) LMNATSHRALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310601-B Fragrance material 高砂香料工业株式会社 2022-05-24 CN disclosed