Toluic Acid

Toluic Acid

SCHEMBL11277682

CCc1ccc(C(=O)O)c(C(=O)O)c1CC.Cc1ccccc1C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 1/20 0.42
MYC P01106 1/20 0.41
ALDH1A1 P00352 5/20 0.41
HPGD P15428 3/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
CLCN2 P51788 2/20 0.40
SLC16A3 O15427 1/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
POLB P06746 1/20 0.39
ALOX15 P16050 1/20 0.38
AKR1C3 P42330 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL10963447 0.91 ALDH1A1 (0.48) CYP3A4CYP2C9KMT2AHTTALDH1A1
Phthalic Acid SCHEMBL29429444 0.91 ALDH1A1 (0.48) CYP3A4CYP2C9KMT2AHTTALDH1A1
SCHEMBL75798 0.87 ALDH1A1 (0.41) KMT2AALDH1A1HPGDKDM4ECLCN2
SCHEMBL17911667 0.85 GABRP (0.40) KMT2AALDH1A1HPGDKDM4ECLCN2
Diethyl Phthalate SCHEMBL8873370 0.85 TSHR (0.60) CYP3A4CYP2C9KMT2AHTTALDH1A1
Diethyl Phthalate SCHEMBL30147367 0.85 TSHR (0.60) CYP3A4CYP2C9KMT2AHTTALDH1A1
Acetic Acid SCHEMBL10946506 0.84 GABRP (0.39) KMT2AALDH1A1HPGDKDM4EHSD17B10
SCHEMBL18038406 0.83 PTPN1 (0.45) CYP3A4CYP2C9ALDH1A1TSHR
SCHEMBL14686370 0.83 SMN1; SMN2 (0.37) CYP3A4CYP2C9KMT2AHTTALDH1A1
SCHEMBL29658282 0.82 LMNA (0.42) KMT2AHTTMYCALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0058888-A2 Conditioning of phthalocyanine compounds MOBAY CHEMICAL CORPORATION (US) 1982-09-01 EP disclosed