Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 5/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662945 | 0.79 | SQOR (0.50) | SQORADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL9084973 | 0.78 | ACHE (0.52) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29788220 | 0.78 | ADORA2A (0.55) | SQORADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL5782038 | 0.78 | ADORA2A (0.55) | SQORADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL29473767 | 0.78 | SQOR (0.50) | SQORALDH1A1HPGDKDM4EMAOA | |
| SCHEMBL29672057 | 0.77 | SQOR (0.55) | SQORADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL18602766 | 0.73 | ACHE (0.46) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL16218972 | 0.73 | NFE2L2 (0.51) | ALDH1A1HPGDKDM4E | |
| SCHEMBL30195961 | 0.72 | FPR2 (0.51) | SQORADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL30195947 | 0.72 | SQOR (0.49) | SQORADORA2AADORA1ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560790-B | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114560790-A | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2022-05-31 | — | — | CN | disclosed |